Public Health Burden

NIH ACTIV vaccine working group weighs role of human challenge studies for SARS-CoV-2 vaccine development

Members of the National Institutes of Health’s Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV) Vaccines Working Group assess practical considerations and prerequisites for using controlled human infection models (CHIMs), which can be used for human challenge studies, to support SARS-CoV-2 vaccine development.

Study finds Ebola survivors in Liberia face ongoing health issues

Survivors of Ebola virus disease (EVD) in Liberia had a higher prevalence of certain health issues — including uveitis (eye redness and pain), abdominal, chest, neurologic, and musculoskeletal abnormalities upon physical exam — when compared to a control group of household and community members who did not have a history of EVD, according to findings from an ongoing study published in the New England Journal of Medicine.